Sex Differences in Gene Expression in Human Adipose Tissue

Sex Differences in Gene Expression in Human Adipose Tissue

This project was created to assess sex differences in adipose tissue gene expression in different locations in the body. The primary objectives are to understand:

1. The mechanisms of differential body fat distribution in men and women
2. How body fat distribution is affected by reproductive hormones
3. The mechanisms linking fat distribution to health risks such as diabetes

Inclusion Criteria:

• Caucasian men and women 20-35 years of age
• Lean (BMI less than 25)
• Obese (BMI 30-35)

Exclusion Criteria:

• Hormonal birth control
• Pregnancy
• Smokers
• History of diabetes, kidney, liver or thyroid disease
• History of cancer