Study never started

Part 1: patients with essential hyperhidrosis are treated one time with suction curettage in both axillae.

Part 2: patients with axillary hyperhidrosis receive one treatment with suction curettage in one axilla, and at the same time one treatment with BOTOX injections in the other axilla.

Inclusion Criteria:

• 18 to 75 years
• Persistent bilateral primary axillary hyperhidrosis
• Hidrosis interferes with daily activities of patient
• Gravimetrically minimal 50 mg spontaneous sweat production in each axilla, measured during 5 minutes in room temperature in calm condition
• signed informed consent
• patient can and shall continue the trial until the end, and will follow the instructions correcly
• women in reproductive period had a pregnancy test

Exclusion Criteria:

• Medical condition that can be dangerous by treatment with BOTOX, including myastenia gravis, Lambert-Eaton syndrome, ALS, and each other disease that can interfere with the neuromuscular function
• Secundary hyperhidrosis (for example secundary on hyperthyroid problems, lymfoma, malaria)
• Known allergy against study medication, his components, local anesthesia or iodium
• Use of aminoglycosids, curare-like products, or other products which can interfere with the neuromuscular function during the study
• Use of therapy for hyperhidrosis with Aluminium chlorid during the study
• Infection or skin disease in the area to treat
• Participation in an other therapeutic study on the same time
• Botuline toxine treatment in the last 4 months
• Women who can or who want to become pregnant
• Women in reproductive period who don't use the appropriate contraception
• Patients in a situation of which the researchers decide it can be dangerous, or can interfere with the study