Triggering of Final Oocyte Maturation With GnRHa (Buserelin) in GnRH Antagonist Cycles

A Prospective Randomised Study to Evaluate the Effect of Triggering Ovulation With GnRHa (Buserelin) and Low Dose hCG (Pregnyl) as Compared to the Use of Conventional Doses of hCG (Pregnyl)

The purpose of this study is to possibly further improve the clinical outcome and explore the incidence of OHSS in patients, who have final oocyte maturation with GnRHa (Buserelin) in GnRH antagonist IVF/ICSI cycles

Inclusion Criteria:

• Patient complying with the conditions for IVF or ICSI treatment
• Female age over 20 years and under 40 years
• Normal regular cycle and patients with oligomenorrhea
• BMI > 18 and < 35
• each patient contributes with one cycle only

Exclusion Criteria:

• Significant disturbances in the woman (diabetes, epilepsy, liver/renal/heart disease, metabolic disorder)
• Patients with > 25 follicles on the day of triggering ovulation