A Prospective, Single Blinded Study for Predicting Colon Polyp Histology With Narrow Band Imaging

A Prospective, Single Blinded Study for Predicting Colon Polyp Histology With Narrow Band Imaging

The investigators hypothesize that NBI will have a high accuracy in predicting polyp histology real time during a colonoscopy by visualization of the surface mucosal and vascular patterns. Aim#1: To determine the sensitivity, specificity and accuracy of NBI and standard white light colonoscopy for predicting polyp histology by evaluating the surface mucosal and vascular patterns during colonoscopy. Aim#2: To determine the inter-observer agreement between investigators for the recognition of various polyp patterns.

Inclusion Criteria:

• referral for screening or surveillance colonoscopy
• the ability to provide informed consent

Exclusion Criteria:

• prior surgical resection of any portion of colon
• prior history of colon cancer
• history of inflammatory bowel disease
• use of anti-platelet agents or anticoagulants that precludes removal of polyps during the procedure
• poor general condition or any other reason to avoid prolonged procedure time
• history of polyposis syndrome or Hereditary Non-polyposis colon cancer
• inability to give informed consent