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| Name | Class |
|---|---|
| Attune Foods | UNKNOWN |
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The study evaluates high fiber diet intake in patients with hyperlipidemia.
Dietary fiber intake has been shown to have modest effect in lowering cholesterol. However, most of these studies were done with 20g/daily fiber intake. Not much is known about high dietary fiber intake (30-40 g/day) and serum cholesterol. Also, there have been small studies that have shown modest decrease in oxidative stress by increasing dietary fiber intake. The goal of our study is to determine the efficacy /safety of high dietary fiber intake in raising HDL, lowering LDL, and lowering oxidative stress in patients with hyperlipidemia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High Fiber Intake | Experimental | Two 3/4 Cup servings of high fiber Uncle Sam cereal daily |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Uncle Sam Cereal | Dietary Supplement | two 3/4 cup servings daily of Uncle Sam Cereal dietary instruction on high fiber diet |
|
| Measure | Description | Time Frame |
|---|---|---|
| To test whether 30-40g of daily dietary fiber increases HDL, lowers total cholesterol and LDL levels in patients at 12 weeks | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| To test whether Lipoprotein (a), triglyceride level, LDL: HDL ratio, fibrinogen, CRP, Urine f1 2 isoprostane and body weight will be lowered in patients after 12weeks. | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Wael A Jaber, MD | The Cleveland Clinic | Principal Investigator |
| Leslie Cho, MD | The Cleveland Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cleveland Clinic | Cleveland | Ohio | 44195 | United States |
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| ID | Term |
|---|---|
| D006949 | Hyperlipidemias |
| ID | Term |
|---|---|
| D050171 | Dyslipidemias |
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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