A Randomised Trial of a Moisturising Cream in Preventing Recurrence of Hand Eczema

A Randomised Trial of a Moisturising Cream in Preventing Recurrence of Hand Eczema

The purpose of this study is to investigate whether a moisturizing cream can prevent hand eczema.Patients with previous hand eczema will be studied. In the second part of the study, it will be explored if a treatment regimen of a topical corticosteroid once daily is not inferior to treatment twice daily.

Inclusion Criteria:

• Clinically proven history of hand eczema
• At inclusion controlled state of hand eczema (≤3 on Hand Eczema Extent Score, HEES)
• Daily use of moisturising treatment
• Either gender
• Age 18 or above
• Written Informed Consent

Exclusion Criteria:

• Possible allergy to ingredients in the study medications
• At study start active psoriatic lesions or active atopic eczema lesions on the hands. Active bacterial, fungal or viral infection of the hands
• Patients who are pregnant or breast-feeding, or who plan to become pregnant during the course of the study
• Use of any concomitant medication that may interfere with the study related activities or assessment of efficacy
• Any patient related factor suggesting potential poor compliance with study procedures (e.g. psychiatric disorders, history of alcohol or substance abuse)
• Any serious medical condition which, in the opinion of the investigator, may interfere with the evaluation of the results
• Inclusion in a study of an investigational drug within 60 days prior to start of treatment