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| ID | Type | Description | Link |
|---|---|---|---|
| UHL ref: 7638 |
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| Name | Class |
|---|---|
| British Heart Foundation | OTHER |
The purpose of this study is to determine whether the administration of patient's own bone marrow cells into scar areas of the heart, can improve the contractile function of these areas.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Active Comparator |
| |
| Intramuscular | Experimental |
| |
| Intracoronary | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Control | Procedure | Coronary artery bypass grafting without bone marrow cells injection |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Contractile function of treated scar areas | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Global left ventricular functions | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Manuel Galiñanes, MD PhD FRCS | University Hospitals, Leicester | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospitals Leicester | Leicester | Leicestershire | LE3 9QP | United Kingdom |
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| Intramuscular administration of bone marrow cells |
| Procedure |
Coronary artery bypass grafting, and intramuscular administration of bone marrow cells into myocardial scar |
|
| Intracoronary administration of bone marrow cells | Procedure | Coronary artery bypass grafting, and intracoronary administration of bone marrow cells into myocardial scar |
|
| ID | Term |
|---|---|
| D009203 | Myocardial Infarction |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |
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