Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack.

Evaluation of Skeletal Myoblast Transplant for Treating Ischemic Heart Failure

Study to examine the safety and effectiveness of implanted skeletal muscle cells (cells removed from the thigh muscle) into scarred areas of heart muscle after heart attack.

Inclusion Criteria:

• Patients recommended for coronary bypass surgery (preferably with cardiopulmonary support)
• Ejection fraction ≥15% and ≤35%
• Left ventricular myocardial infarction (MI - heart attack) ≥4 weeks prior to screening

Exclusion Criteria:

• Need for a rapid surgical coronary revascularization
• Need for any other related cardiosurgical measure during coronary surgery (e.g. mitral valve repair or valve replacement)
• Patients with a left ventricular aneurysm who is a candidate for left ventricular aneurysmectomy or left ventricular reduction surgery; patient receiving left or biventricular (BiV) pacing therapy for heart failure (unless the patient has stabilized after 6 or more months of this therapy)
• Cardiomyopathy presumed to be of non-ischemic origin