Irbesartan Effects on Endothelial Dysfunction in Hypertensive Type II Diabetic Patients Comparing Atenolol

Irbesartan Effects on Endothelial Dysfunction in Hypertensive Type II Diabetic Patients Comparing Atenolol

To show that Irbesartan improves endothelial dysfunction and the procoagulant state which are thought to be the possible mechanisms, inducing a generalized vasculopathy associated with microalbuminuria and vascular events in type II diabetic hypertensive patients

Inclusion Criteria:

• non insulin dependent type II manifest diabetes with glycosilated HbA1c levels over %6.5-8
• mild to moderate hypertension stage I and stage II according to ESC-ESH 2003 (140-180 mmHg)

Exclusion Criteria:

• congestive heart failure
• azotemia
• insulin dependent diabetes
• liver insufficiency
• pregnancy
• cancer

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.