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| ID | Type | Description | Link |
|---|---|---|---|
| P30CA043703 | U.S. NIH Grant/Contract | View source | |
| CASE5506 | Other Identifier | Case Comprehensive Cancer Center | |
| CASE-5506-CC217 |
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| Name | Class |
|---|---|
| National Cancer Institute (NCI) | NIH |
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RATIONALE: Learning about the effects of radiation therapy on the body's muscles, organs, and bones in patients with stage III non-small cell lung cancer may help doctors plan the best treatment.
PURPOSE: This clinical trial is studying the effects of radiation therapy on the body in patients with stage III non-small cell lung cancer.
OBJECTIVES:
Primary
OUTLINE: Patients receive radiotherapy as planned for 7 weeks. Patients undergo an interview on treatment day 1 (before initiation of radiotherapy) and treatment day 35 (after completion of radiotherapy) regarding recent food consumption history and appetite. Patients' standing weight and height are measured on these days and their body composition, measured with a bioelectrical impedance analysis (BIA) device, are also taken. Patients' Karnofsky performance score are obtained from their medical record.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| physiologic testing | Other | |||
| questionnaire administration | Other | |||
| management of therapy complications | Procedure | |||
| radiation therapy | Radiation |
| Measure | Description | Time Frame |
|---|---|---|
| Energy and protein consumption measured on an average radiotherapy treatment day by multiple pass method 24-hour analysis for food recall at baseline and treatment end | ||
| Comparison of energy and protein by mouth intake from baseline to treatment end | ||
| Comparison of diet quality as measured by Healthy Eating Index (HEI) score from baseline to treatment end | ||
| Lean body mass versus fat mass using a bioelectrical impedance analysis machine | ||
| Comparison of body fat to lean body mass percentage at baseline and at treatment end | ||
| Correlation of energy and protein consumption with lean body mass at baseline and treatment end | ||
| Change in appetite throughout radiotherapy determined by interview at baseline and end of treatment | ||
| Change in performance level (Karnofsky percentage) associated with the radiotherapy procedure determined by questions asked at baseline and end of treatment |
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DISEASE CHARACTERISTICS:
Diagnosed with stage III non-small cell lung cancer (NSCLC)
Plan to begin radiotherapy for NSCLC
No brain metastases
PATIENT CHARACTERISTICS:
Inclusion criteria:
Exclusion criteria:
PRIOR CONCURRENT THERAPY:
Exclusion criteria:
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Primary care center
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| Name | Affiliation | Role |
|---|---|---|
| Jessica Stauffer, BS | Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center | Cleveland | Ohio | 44106-5065 | United States |
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| Label | URL |
|---|---|
| Clinical trial summary from the National Cancer Institute's PDQ® database | View source |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| D044342 | Malnutrition |
| D001836 | Body Weight Changes |
| D002289 | Carcinoma, Non-Small-Cell Lung |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D002283 | Carcinoma, Bronchogenic |
| D001984 | Bronchial Neoplasms |
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| ID | Term |
|---|---|
| D011878 | Radiotherapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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