Novel nutrition program :

Give nutrition health education every week and regular survey and intervention. The education booklets are made based on the guideline and characteristics of the disease.

Routine nutrition education Give nutrition education if the patient visits the clinics. Irregular survey and intervention were given to the patients.

Give nutrition health education every two weeks and regular survey and intervention. The education booklets are made based on the guideline and characteristics of the disease.

Nutrition Risk Screening 2002 is used to assess the risk of malnutrition.

Body mass index is a measure of body fat based on height and weight that applies to adult men and women. It equals to weight divided by height square.

level of serum albumin

The QOL was measured by the European Organization for Research and Treatment quality of life version 3 questionnaire (EORTC QLQ-C30) simplified Chinese version. It contains five functional scales (physical, role, cognitive, emotional, and social), three symptoms scales (fatigue, pain, and nausea and vomiting), a global health scale, a number of single items assessing additional symptoms commonly reported by cancer patients (dyspnea, appetite loss, insomnia, constipation, and diarrhea) and financial impact of the disease. For most items, four response categories from 1 (not at all) to 4 (very much) are employed; two items (overall health, overall quality of life) have response categories ranging from 1 to 7. A high scale score represents a higher response level. Thus a high score for a functional scale, the global health status or overall QOL represents a high or healthy status or a high QOL; however, a high score for the symptom scales represents a high level of symptom.

Using Eastern Cooperative Oncology Group to assess the physical function.

Knowledge Scale composes of 10 questions and 10 scores for each question. Attitude and Practice Scale have 5 questions. Each question is rated as A、B、C. A represents 20 score and B is 10 score.