Prophylaxis of Ventilator Associated Pneumonia by Continuous Lateral Rotation Therapy

Prophylaxis of Ventilator Associated Pneumonia by Continuous Lateral Rotation Therapy

Hypothesis: Ventilator associated pneumonia (VAP) in critically ill patients may be prevented by continuous lateral rotation therapy (CLRT) using specially designed, motor driven beds.

Patients are randomized to CLRT or supine position if mechanically ventilated and not suffering from pneumonia or ARDS within 48 hours after intubation. Prophylaxis of VAP is standardized in both groups. Primary endpoint is incidence of VAP, secondary endpoints are length of ventilation, length of stay and mortality.

Inclusion Criteria:

• Mechanically ventilated
• Intubated not longer than 48 h
• Medical cause for ICU admission
• Expected to be ventilated for > 48 hours

Exclusion Criteria:

• Pneumonia or ARDS present
• Postoperative patient