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Aim of this study is to investigate whether patients preoperatively treated with acetylsalicylic acid and/or clopidogrel have fewer perioperative bleeding and lower amounts of blood substitution when managed by ROTEM (whole blood coagulation analyzer) and MULTIPLATE (thrombocyte function analyzer).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Point-of-Care managed | This arm includes all patients in which the hemostatic therapy is guided by POC devices e.g. MULTIPLATE (a platelet function analyzer) or ROTEM (thromboelastometry) | ||
| Conventional hemostasis lab managed | This arm includes all patients in which the hemostatic therapy is guided by conventional hemostasis laboratory data e.g. INR, aPTT, fibrinogen concentration, platelet count but no POC devices e.g. MULTIPLATE (a platelet function analyzer) or ROTEM (thromboelastometry) |
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| Measure | Description | Time Frame |
|---|---|---|
| Perioperative blood loss | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| perioperative substitution with erythrocyte concentrates, thrombocyte concentrates or fresh frozen plasma | 24 hours and 7 days |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergoing cardiac surgery
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| Name | Affiliation | Role |
|---|---|---|
| Miodrag Filipovic, PhD, MD | Department of Anesthesia, University Hospital Basel, CH-4031 Basel, Switzerland | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Basel | Basel | CH | 4031 | Switzerland |
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| ID | Term |
|---|---|
| D001778 | Blood Coagulation Disorders |
| ID | Term |
|---|---|
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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