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| Name | Class |
|---|---|
| Top Institute Food and Nutrition | OTHER |
| SEAMEO-TROPMED RCCN University of Indonesia | UNKNOWN |
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This is a long term study on the efficacy of dietary calcium with or without probiotic strains in reducing the mean number of episodes and duration of diarrheal disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Placebo Comparator |
| |
| 2 | Active Comparator |
| |
| 3 | Active Comparator |
| |
| 4 | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| low calcium milk of 180 ml | Dietary Supplement | twice daily for 24 weeks |
| |
| Measure | Description | Time Frame |
|---|---|---|
| The mean number of episodes and duration of acute diarrheal disease | 24 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of acute diarrheal disease | 24 weeks | |
| Severity of acute diarrheal disease | 24 weeks | |
| Intestinal and systemic inflammation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Rina Agustina, MD | SEAMEO-TROPMED RCCN UI | Principal Investigator |
| Frans J. Kok, Prof | Division of Human Nutrition, Wageningen University (WUR) | Study Chair |
| Ingeborg Bovee-Oudenhoven, PhD | TIFN/ NIZO Food Research | Study Director |
| Agus Firmansyah, Prof, MD | Faculty of Medicine University of Indonesia | Study Chair |
| Widjaja Lukito, MD | SEAMEO-TROPMED RCCN UI | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seameo-Tropmed Rccn Ui | Jakarta | Jakarta Special Capital Region | 10430 | Indonesia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23700339 | Derived | Agustina R, Bovee-Oudenhoven IM, Lukito W, Fahmida U, van de Rest O, Zimmermann MB, Firmansyah A, Wulanti R, Albers R, van den Heuvel EG, Kok FJ. Probiotics Lactobacillus reuteri DSM 17938 and Lactobacillus casei CRL 431 modestly increase growth, but not iron and zinc status, among Indonesian children aged 1-6 years. J Nutr. 2013 Jul;143(7):1184-93. doi: 10.3945/jn.112.166397. Epub 2013 May 22. | |
| 22492764 |
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| ID | Term |
|---|---|
| D003967 | Diarrhea |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D019936 | Probiotics |
| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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| regular milk of 180 ml |
| Dietary Supplement |
twice daily for 24 weeks |
|
| regular milk of 180 ml + probiotics | Dietary Supplement | twice daily for 24 weeks |
|
| regular milk of 180 ml + probiotics | Dietary Supplement | twice daily for 24 weeks |
|
| 24 weeks |
| Intestinal colonization with pathogenic bacteria or viruses | 24 weeks |
| Nutritional status based on anthropometric measurement | 24 weeks |
| Iron and zinc status | 24 weeks |
| Incidence, mean episodes and duration of acute respiratory infections | 24 weeks |
| Derived |
| Agustina R, Kok FJ, van de Rest O, Fahmida U, Firmansyah A, Lukito W, Feskens EJ, van den Heuvel EG, Albers R, Bovee-Oudenhoven IM. Randomized trial of probiotics and calcium on diarrhea and respiratory tract infections in Indonesian children. Pediatrics. 2012 May;129(5):e1155-64. doi: 10.1542/peds.2011-1379. Epub 2012 Apr 9. |
| D019602 |
| Food and Beverages |