GnRH Agonist and Intrauterine Insemination

Effect of GnRH Agonist Administration at the Time of Implantation in Intrauterine Insemination Cycles: A Randomized Controlled Trial

The aim of this study is to assess whether GnRH agonist administration in the luteal phase improves pregnancy outcome in intrauterine insemination (IUI) cycles.

Inclusion Criteria:

• Women < 38 years old
• Bilateral tubal patency confirmed by hysterosonography
• Normal ultrasound scan of uterus and ovaries
• Normal day 3 basal hormones
• Motile sperm count after capacitation ≥ 3 mill/ml

Exclusion Criteria:

• Endometriosis
• Polycystic ovary syndrome
• Uterine disease (polyps, myomas and müllerian diseases)