Early Diagnosis, Pathogenesis and Progression of Open Angle Glaucoma

Glaucoma Including Pseudoexfoliation Syndrome (SFB 539)

The Erlangen Glaucoma Registry is a clinical registry for cross sectional and longitudinal observation of patients with open angle glaucoma (OAG) or glaucoma suspect, founded in 1991. The primary aim is the evaluation of diagnostic and prognostic validity of morphometrical, sensory and hemodynamical diagnostic procedures. No therapeutic studies are performed.

Purpose: Detection of onset and progression of structural and functional damage due to glaucoma. Determination of rate and amount of progressive change due to glaucoma. Characterisation of the relationship between structural and functional change over time. Evaluation of predictive factors for the development and progression of glaucoma.

Participants:

• Patients: Primary open angle glaucoma, secondary open angle glaucoma due to PEX or MDS, glaucoma suspects including ocular hypertension
• Healthy volunteers (for cross sectional analysis only)

Inclusion Criteria:

• Open anterior chamber angle
• Best corrected visual acuity 0.7 or better
• Age between 18 and 65 years

Exclusion Criteria:

• Any eye disease other than glaucoma
• Systemic diseases with potentially ocular involvement (e.g., diabetes mellitus)
• Myopic or hyperopic refractive error exceeding 8.0 diopters