Study of Antibiotic Utilization Measures and Control of ESBLs in China

Association of Antibiotic Utilization Measures and Control of Extended-spectrum β-lactamases (ESBLs) in MICU1 and MICU2 at Buddhist Tzu Chi General Hospital.

A single-center, prospective, comparative, antibiotic intervention study for patients admitted to MICU1 and MICU2

1. To determine the value of using β-lactamases inhibitors in reducing the cases of ESBL producing E. coli or K. pneumoniae colonization and infection after 12 months.
2. To compare the acquisition rates of ESBL producing E. coli or K. pneumoniae at MICU1 and MICU2 after 12 months

Inclusion Criteria:

• All patients admitted or transferred to the ICU/burn units.
• Patients of either sex, 18 years of age or older.

Exclusion Criteria:

• Patient with hypersensitivity to penicillins, cephalosporins, and beta-lactamase inhibitors.