Study Evaluating Antibiotic Utilization Measures and Control of Extended-Spectrum-Lactamases (ESBLs)

Association of Antibiotic Utilization Measures and Control of Extended-spectrum-lactamases (ESBLs)

• To determine the value of using piperacillin/tazobactam in reducing the cases of ESBL producing E. coli or K. pneumoniae colonization and infection.
• To determine the acquisition rate of ESBL producing E. coli or K. pneumoniae, both pre and post intervention in the selected medical centers.

Inclusion Criteria:

• Patients admitted or transferred to the ICU/pulmonary/hematology units.
• Patients of either sex, 18 years of age or older

Exclusion Criteria:

• Pregnant and nursing women. Female of childbearing potential without using any birth control methods. Female of childbearing potential using oral contraceptives during study period. (Note: penicillin and beta-lactamase inhibitors may prevent oral contraceptives from working properly, increasing the chance of pregnancy).
• Patients who have the contraindications of using Tazocin (pipercillin/tazobactam)

Other exclusions apply.