Analysis of Human Tear Proteins in Children

Analysis of Human Tear Proteins in Children: A Pilot Study to Describe the Tear Film Proteome of Pediatric Patients Undergoing Ophthalmic Examination.

The significance of our study is in the importance of understanding the quality and quantity of proteins in the human tear film, and any unique aspects of tears in children. This pilot study will provide data to plan prospective research to better delineate the utility of tear proteins in diagnosing and following disease status in a non-invasive fashion.

Inclusion Criteria:

• Less than 18 years of age
• A parent or legal guardian provide written informed consent to participate
• Able to cooperate with tear sample collection, or a previously planned sedation for other medical purposes

Exclusion Criteria:

• Age greater than or equal to 18 years
• Patients' parents or legal guardians who refuse to sign study consent