Coagulation Parameters During Pregnancy in Amniotic Fluid

Coagulation Parameters During Pregnancy in Amniotic Fluid

Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.

Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.

Inclusion Criteria:

• Women undergoing amniocentesis during 15-35 weeks of gestation.

Exclusion Criteria:

• A history of venous thromboembolism
• Systemic disease i.e.; diabetes, hypertension, hypo or hyper-thyroidism,
• Anticoagulant treatment
• Abnormal embryo