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The purpose of this study is to determine the ability of a proprietary software screening tool to discriminate normal corneas (front surface of the eye) from previously diagnosed corneal conditions (diseases/surgeries/pathologies) and to determine the repeatabiltity and reproducibility of the Atlas II corneal topographer in normal human corneas.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Normals |
| ||
| Keratoconus |
| ||
| Myopic Laser Vision Correction | Patients who have undergone myopic:
| ||
| Hyperopic Laser Vision Correction | Patients who have undergone hyperopic:
| ||
| Orthokeratology | 1. Patients using specially designed rigid contact lenses to reshape the cornea to temporarily reduce or eliminate refractive error. | ||
| Others |
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| Measure | Description | Time Frame |
|---|---|---|
| Reference values of normal and previously diagnosed corneal conditions by Atlas II corneal topographer | 1-2 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Repeatabiltity and reproducibility of the Atlas II corneal topographer in human corneas | 1-2 hours |
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Inclusion Criteria:
Normals
Keratoconus
Myopic Laser Vision Correction
Patients who have undergone myopic:
Hyperopic Laser Vision Correction
Patients who have undergone hyperopic:
Orthokeratology
Exclusion Criteria:
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Subjects will consist of patients seeking consult in the Principal Investigator's (PI) clinical practice and volunteers responding to the study's advertisements.
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| Name | Affiliation | Role |
|---|---|---|
| Jon Dishler, M. D. | Dishler Laser Institute | Principal Investigator |
| David J Schanzlin, M. D. | Shiley Eye Center-University of California San Diego | Principal Investigator |
| Dennis Burger, O. D. | Kaiser Permanente, Oakland | Principal Investigator |
| Patrick Caroline, COT | Pacific University | Principal Investigator |
| Tyson Brunstetter, O. D. | Naval Training Center-Refractive Surgery Clinic | Principal Investigator |
| Kevin Reeder, O.D. | Carmel Mountain Vision Care Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shiley Eye Center-University of California San Diego | La Jolla | California | 92093 | United States | ||
| Carmel Mountain Vision Care Center |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 9856763 | Background | Zadnik K, Barr JT, Edrington TB, Everett DF, Jameson M, McMahon TT, Shin JA, Sterling JL, Wagner H, Gordon MO. Baseline findings in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study. Invest Ophthalmol Vis Sci. 1998 Dec;39(13):2537-46. | |
| 16357645 | Background | Twa MD, Parthasarathy S, Roberts C, Mahmoud AM, Raasch TW, Bullimore MA. Automated decision tree classification of corneal shape. Optom Vis Sci. 2005 Dec;82(12):1038-46. doi: 10.1097/01.opx.0000192350.01045.6f. |
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| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| D007640 | Keratoconus |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
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1. Corneal conditions (diseases/ pathologies/surgeries) that can potentially affect the corneal surface that are not listed above (e.g. pellucid marginal degeneration; postoperative corneal transplant, intra-corneal ring segments, refractive keratotomy, conductive keratoplasty; peripheral ulcerative keratitis, Terrien's marginal degeneration; etc.). |
| San Diego |
| California |
| 92129 |
| United States |
| Dishler Laser Institute | Greenwood Village | Colorado | 80111 | United States |
| Pacific University | Forest Grove | Oregon | 97116 | United States |