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Heartburn, a burning sensation in the chest or throat, occurs in many patients when acidic stomach contents move into the esophagus from the stomach. This study will investigate the safety and efficacy of lansoprazole 15 mg once a day in treating frequent heartburn.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lansoprazole | Drug |
| Measure | Description | Time Frame |
|---|---|---|
| To demonstrate that repeated daily doses of 15 mg of lansoprazole are effective in increasing the proportion of days with no heartburn during study treatment, when compared to placebo. |
| Measure | Description | Time Frame |
|---|---|---|
| To determine the proportion of nighttimes with no heartburn during 14 days of treatment in subjects receiving lansoprazole versus placebo | ||
| To determine the proportion of subjects with no heartburn during day 1 in those receiving lansoprazole versus placebo |
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Inclusion Criteria:
Exclusion Criteria:
Other protocol-defined inclusion or exclusion criteria may apply.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sunbelt Research Group | Mobile | Alabama | 36608 | United States | ||
| Arkansas Primary Care Clinic |
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| Evaluation of lansoprazole safety. |
| Little Rock |
| Alaska |
| 72204 |
| United States |
| Radiant Research | Chandler | Arizona | 85225 | United States |
| Radiant Research - Scottsdale | Scottsdale | Arizona | 85251 | United States |
| Edinger Medical Group | Fountain Valley | California | 92709 | United States |
| Gaslamp Medical Center | San Diego | California | 92101 | United States |
| Expresscare Clinical Research | Colorado Springs | Colorado | 80909 | United States |
| Central Florida Clinical Trials inc. | Altamonte Springs | Florida | 32714 | United States |
| Tampa Bay Medical Research, Inc. | Clearwater | Florida | 33761 | United States |
| Health Awareness Inc. | Jupiter | Florida | 33458 | United States |
| University Clinical Research, Inc. | Pembroke Pines | Florida | 33024 | United States |
| Palm Beach Research | West Palm Beach | Florida | 33409 | United States |
| Accelovance | Peoria | Illinois | 61602 | United States |
| IRSI | Rockland | Massachusetts | 04841 | United States |
| Prime Care Research | St Louis | Missouri | 63031 | United States |
| Clinical Research Center of Nevada | Las Vegas | Nevada | 89104 | United States |
| Urgentmed | South Bound Brook | New Jersey | 08880 | United States |
| Wake research associates, Inc | Raleigh | North Carolina | 27612 | United States |
| Piedmont Medical Research | Winston-Salem | North Carolina | 27103 | United States |
| Radiant Research | Cincinnati | Ohio | 45236 | United States |
| Wells Institute For Health Awareness | Kettering | Ohio | 45429 | United States |
| Toledo Center for Clinical Research | Sylvania | Ohio | 43560 | United States |
| Durham Physicans | Durham | Pennsylvania | 19047 | United States |
| 2222 State Street | Nashville | Tennessee | 37203 | United States |
| Wells Branch Medical Center | Austin | Texas | 78728 | United States |
| Medical Edge Healthcare Group | Dallas | Texas | 75243 | United States |
| Houston | Texas | 77002 | United States |
| Clinical Trials Network | Houston | Texas | 77074 | United States |
| Health Research of Hampton Roads | Newport News | Virginia | 23606 | United States |
| Holston Medical Group | Weber City | Virginia | 24290 | United States |
| ID | Term |
|---|---|
| D006356 | Heartburn |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D064747 | Lansoprazole |
| ID | Term |
|---|---|
| D053799 | 2-Pyridinylmethylsulfinylbenzimidazoles |
| D013454 | Sulfoxides |
| D013457 | Sulfur Compounds |
| D009930 | Organic Chemicals |
| D011725 | Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D001562 | Benzimidazoles |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
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