Efficacy of Esomeprazole in Patients With Frequent Heartburn

A Phase III Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of 14 Day Treatment With Esomeprazole 20 mg Once Daily in Subjects With Frequent Heartburn

This study will investigate the efficacy of esomeprazole 20 mg once a day in the treatment of frequent heartburn

Inclusion Criteria:

• Males and non-pregnant ,non-lactating females 18 years or older
• Experience heartburn at least 2 days a week
• Having heartburn that has responded to heartburn medication
• Must discontinue any current heartburn medications

Exclusion Criteria:

• Having a history of erosive esophagitis verified by endoscopy
• Having a history of GERD which was diagnosed by a physician
• Inability to take study medication or complete the study and all study procedures
• Subjects that have required more than one 14-day course of PPI treatment within the past 4 months