Descriptive Study of Pain, Anxiety and Depression

Pain, Anxiety and Depression in Chronic Pain Patients With and Without Neuropathic Pain Compared With Healthy Volunteers

The purpose of the study is to investigate pain, anxiety and depression in chronic pain patients with and without neuropathic pain compared with healthy volunteers

Primary outcome measures:

• Symptom checklist 92

Secondary outcome measures:

• Hamilton Depression and Anxiety Rating Scale
• Major Depression Inventory
• GAD-10 Anxiety Scale
• Health Survey SF-36
• McGill Pain Questionnaire
• Sweat test
• Heart rate variability testing
• Coping Strategy Questionnare
• Quantitative sensory testing
• Pain Catastrophizing Scale
• Pain rating (VAS)
• Interview

Inclusion Criteria:

• Neuropathic pain patient or patient with fibromyalgia
• Daily pain in more than 6 months
• Weekly average pain score 4 or more (VAS)

Exclusion Criteria:

• Treatment with antidepressants, anticonvulsants or any other pain medication except paracetamol
• Serious or unstable medical disease
• Prior or present diagnosis of mania, bipolar or psychotic disorder, delirium, suicidal, drug and alcohol dependence, severe agitation
• Patients who cannot cooperate and do not understand Danish