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The aim of this study is to compare the safety and efficacy of conventional and micropulse transscleral diode laser in the treatment of end-stage glaucoma.
End-stage glaucoma is difficult to treat, and it may sometimes be unresponsive to surgery or medications. A common treatment is the conventional transscleral cyclophotocoagulaion, but it has various side effects. This study specifically aims to compare the intraocular pressure (IOP) lowering effects and the incidence of complications such as hypotony, phthisis, sympathetic ophthalmia, surface conjunctival burns, bulbar conjunctival swelling, decompensation of corneal grafts, hyphema and vitreous hemorrhage, in conventional and the newer micropulse transscleral cyclophotocoagulation.The hypothesis is that the micropulse transscleral cyclophotocoagulation will be as good or better than the conventional transscleral cyclophotocoagulation, with less complications.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Micropulse Transscleral Cyclophotocoagulation | Procedure | |||
| Conventional Transscleral Cyclophotocoagulation | Procedure |
| Measure | Description | Time Frame |
|---|---|---|
| Number of patients in each group that had a 30% decrease of IOP from baseline after 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Number of patients with complications, such as hypotony, phthisis, sympathetic ophthalmia, surface conjunctival burns, bulbar conjunctival swelling, decompensation of corneal grafts, hyphema and vitreous hemorrhage |
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Inclusion Criteria:
· More than 21 years old
Exclusion Criteria:
· Any eye surgery done within 2 months of enrolment
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anna Tan, MMed | Contact | 6772-5317 | amwttan@yahoo.com | |
| Grace Dizon, MD | Contact | 6772-5317 | gengmd@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Paul Chew, FRCSEd,MMed | National University Hospital,Ophthalmology Department | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National University Hospital Singapore Department of Ophthalmology | Recruiting | Singapore | 119074 | Singapore |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 9142680 | Background | Berger JW. Thermal modelling of micropulsed diode laser retinal photocoagulation. Lasers Surg Med. 1997;20(4):409-15. doi: 10.1002/(sici)1096-9101(1997)20:43.0.co;2-u. | |
| 12213158 | Background | Ho CL, Wong EY, Chew PT. Effect of diode laser contact transscleral pars plana photocoagulation on intraocular pressure in glaucoma. Clin Exp Ophthalmol. 2002 Oct;30(5):343-7. doi: 10.1046/j.1442-9071.2002.00553.x. |
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| ID | Term |
|---|---|
| D005901 | Glaucoma |
| ID | Term |
|---|---|
| D009798 | Ocular Hypertension |
| D005128 | Eye Diseases |
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