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| Name | Class |
|---|---|
| Matthew Caldwell | UNKNOWN |
The purpose of this study is to compare healing times and subjective pain level responses of nepafenac to placebo after photo refractive keratomileusis (PRK) surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nevanac | Experimental | One drop, three times daily, in the assigned eye for the first three postoperative days |
|
| Acular LS | Placebo Comparator | One drop, three times daily, in the assigned eye for the first three postoperative days |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| nepafenac 0.1% | Drug | Nepafenac 0.1% randomly assigned to one eye, with ketorolac 0.4% in the fellow eye for contralateral post-surgical use. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Subjective pain | Day 5 |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of epithelial healing | Time to event |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Matthew Caldwell | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lackland Air Force Base | San Antonio | Texas | 78236 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18500088 | Result | Caldwell M, Reilly C. Effects of topical nepafenac on corneal epithelial healing time and postoperative pain after PRK: a bilateral, prospective, randomized, masked trial. J Refract Surg. 2008 Apr;24(4):377-82. doi: 10.3928/1081597X-20080401-11. |
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| ketorolac 0.4% | Other | Keterolac 0.4% randomly assigned to one eye, with nepafenac 0.1% in the fellow eye for contralateral post-surgical use. |
|