Clinical Trial Comparing Tissue Adhesive Vs. Absorbable Suture Vs. Non-Absorbable Suture

A Randomized Clinical Trial Comparing Tissue Adhesive (2-Octylcyanoacrylate) Vs. Absorbable Suture Vs. Non-Absorbable Suture for the Closure of Low Tension Facial and Neck Wounds in Children and Adolescents

Standard suture is superior to both tissue adhesive (2-octyl cyanoacrylate) and absorbable sutures with respect to cosmetic outcome of, complication rate of and parental satisfaction with the closure of low tension facial, neck and shoulder, wounds in children and adolescents

Inclusion Criteria:

• Age less than or equal to 18
• Pre-operative diagnosis of cyst or pilomatrixoma of neck, face or shoulder
• outpatient scheduled for outpatient or day surgery at Children's Hospital San Diego

Exclusion Criteria:

• known hypersensitivity to cyanoacrylate or formaldehyde
• lesions with any evidence of active infection or gangrene
• lesions on or across mucocutaneous surfaces
• lesions in which skin may be regularly exposed to body fluids
• lesions located in areas of dense natural hair (ie scalp)
• patients with peripheral vascular disease, insulin dependent diabetes mellitis or blood clotting disorders
• patients with known immunodeficiencies
• inability to return for follow-up