A 24-month, Double-blind, Randomized, Multicenter, Placebo-controlled, Parallel-group Study Comparing the Efficacy and Safety of Fingolimod 1.25 mg and 0.5 mg Administered Orally Once Daily Versus Placebo in Patients With Relapsing-remitting Multiple Sclerosis
A 24-month, Double-blind, Randomized, Multicenter, Placebo-controlled, Parallel-group Study Comparing the Efficacy and Safety of Fingolimod 1.25 mg and 0.5 mg Administered Orally Once Daily Versus Placebo in Patients With Relapsing-remitting Multiple Sclerosis
This study assessed the efficacy, safety, and tolerability of 2 doses of oral fingolimod (1.25 mg/day and 0.5 mg/day) compared to placebo in patients with relapsing-remitting multiple sclerosis (RRMS)
Inclusion Criteria:
Exclusion Criteria:
Other protocol-defined inclusion/exclusion criteria applied to this study.
Route de Lennik 808, Brussels Capital 1070, Belgium
Boulevard Paul Janson 92, Charleroi 6000, Belgium
Department Neurology, Herestraat 49, Leuven 3000, Belgium
Department of Neurology & Rehab-Umit, Gentsesteenweg 132, Sijsele 8340, Belgium
St.Trudo, Diestersteenweg 100,, St.Truiden 3800, Belgium
Trillium Health Center, 00 Queesway West, Mississauga, Ontario L5B 1B8, Canada
Department of Neurology, Zabrdovicka 3, Brno 63600, Czechia
First Department of Neurology, Pekarska 53, Brno 65691, Czechia
Department of Neurology, I.P. Paulova 6, Olomouc 77520, Czechia
Department of Neurology, Kyjevska 44, Pardubice 53203, Czechia
Department of Neurology, Alej Svobody 80, Plzeň 3046, Czechia
Department of Neurology, V Uvalu 84, Prague 5 15006, Czechia
MS Centrum, Neurologicka Klinika, Karlovo Namesti 32, Praha 2 12808, Czechia
Neurology Department of Hospital Teplice, Duchcovska 53, Teplice 41529, Czechia
Mannnerheiminaukio 1 B 2 Floor, Helsinki 0100, Finland
Brahenkatu 11 D,, Turku 20100, Finland
Service Neurologie, Boulevard Jean Moulin, Marsielle Cedex 5, 13385, France
Seesen/Harz, 38723, Germany
Mesogeion 154 Ave., Athens, 11527, Greece
Terma Zaimi, Melissia-Athens, 15127, Greece
Thessaloniki, 54636, Greece
Tel Hashomer, Ramat-Gan,, 52621, Israel
De Boelelaan 1118, Amsterdam 1081, Netherlands
Postbus 2500, Nieuwegein 3430 EM, Netherlands
Heiweg 97, Nyimegen 6533, Netherlands
Dr. Molewaterplein 40, Rotterdam 3015 GD, Netherlands
Hilvarenbeekse Weg 60, Tilburg 5022, Netherlands
Walramstraat 23, BK Sittard, 6131, Netherlands
Klinika Neurologii, Ul. Marii Skłodowskiej-Curie 24 A, Bialystok 15-276, Poland
Ul. Swietego Mikolaja 1/8, Bialystok 15-420, Poland
Mozgu, Nowe Ogrody 1/6, Gdańsk 80-803, Poland
Ul. Medykow 14, Katowice 40-752, Poland
Department of Neurology, Ul. Przybyszewskiego 49, Poznan 60-355, Poland
Department of Neurology, Wołoska 137, Warsaw 02-507, Poland
II Klinika Neurologii, Ul. Sobieskiego 1/9, Warsaw 02-957, Poland
MSWiAw Warszawie, Woloska 137, Warszawa 00-909, Poland
Ul. Banacha 1A, Warszawa 01-097, Poland
Moscow, 121356, Russia
Saint Petersburg, Russia
Limbová 5, Bratislava Region 833 05, Slovakia
Mickiewiczova 13, Bratislava, 813 69, Slovakia
E 8-74, Groote Schuur Hospital, Observatory Cape Town, 7925, South Africa
Sandton, 2196, South Africa
Forskningsenhet, SU/Östra CKÖ Plan 0, Gothenburg 41345, Sweden
Neuroimmunology Unit, CMM L8:04, Stockholm, 171 76, Sweden
Neurology-Neurosurgical, Petersgraben 4, Basel 4031, Switzerland
Rue Du Bugnon, Lausanne 1011, Switzerland
Department of Neurology, Ankara, Turkey (Türkiye)
Medical Faculty Neurology Department, Besevler Ankara 06500, Turkey (Türkiye)
Medical Faculty Hospital Neurolgy Department, Bornova Izmir 35100, Turkey (Türkiye)
Departement of Neurology, Capa Istanbul 34093, Turkey (Türkiye)
Department of Neurology, Cerrahpasa Istanbul 34098, Turkey (Türkiye)
Neurology Department, Gaziantep 27070, Turkey (Türkiye)
Tip Fakultesi, Noroloji ABD, Görükle / Bursa, Turkey (Türkiye)
Hospital Neurology Service, 35120 Gaziler Cad. Izmir, Turkey (Türkiye)
Inciralti, Izmir, 35340, Turkey (Türkiye)
Noroloji Klinigi, Göztepe Istanbul, 34722, Turkey (Türkiye)
P041 Institute of Psychiatry, Denmark Hill, London SES 8AF, United Kingdom
Division of Clinical Neurology Medical School, Nottingham NG7 24H, United Kingdom
Glossop Road, Sheffield S102JF, United Kingdom
Backshaw Road, London, Tooting London SW17 0QT, United Kingdom