A 12-month Double-blind, Randomized, Multicenter, Active-controlled, Parallel-group Study Comparing the Efficacy and Safety of 0.5 mg and 1.25 mg Fingolimod (FTY720) Administered Orally Once Daily Versus Interferon ß-1a (Avonex) Administered im Once Weekly in Patients With Relapsing-remitting Multiple Sclerosis With Optional Extension Phase
A 12-month Double-blind, Randomized, Multicenter, Active-controlled, Parallel-group Study Comparing the Efficacy and Safety of 0.5 mg and 1.25 mg Fingolimod (FTY720) Administered Orally Once Daily Versus Interferon ß-1a (Avonex) Administered im Once Weekly in Patients With Relapsing-remitting Multiple Sclerosis With Optional Extension Phase
This study assessed the safety, tolerability, and efficacy of 2 doses of oral fingolimod versus interferon β-1a to reduce the frequency of relapses in patients with relapsing-remitting multiple sclerosis.
Inclusion Criteria:
Exclusion Criteria:
Other protocol-defined inclusion/exclusion criteria applied to the study.
Fairfield, Connecticut 06824, United States
Lenexa, Kansas 66214, United States
St Louis, Missouri 63110, United States
Bristol, Tennessee 37620, United States
Milwaukee, Wisconsin 53215, United States
Guarda Vieja 4435, Capital Federal, Buenos Aires 1428, Argentina
General Urquiza 609, Buenos Aires, C1221ADC, Argentina
Department of Medicine, Level, Missenden R, Camperdown, New South Wales 2050, Australia
Liverpool, New South Wales 2170, Australia
Suite 30, Grattan St., Parkbville, Victoria 3050, Australia
Vancouver, British Columbia V56 2X6, Canada
Toronto, Ontario M5B 1W8, Canada
Fleurimont, Quebec J1H 5N4, Canada
Erbach/Odenwald, 64711, Germany
Voutes, Heraklion, Crete GR 71001, Greece
Patra - RIO, GR- 26500, Greece
Thessaloniki, GR 54636, Greece
Piazza Giulio Cesare, 11 Bari, 70124, Italy
Via Conca, 71, Torrette Di Ancona, 60020, Italy
Via Dei Vestini, 5 Chieti, 66100, Italy
Via Di Grottarossa, 1035/1039, Roma, 00189, Italy
Viale Giovan Battista Morgagni, 85, Firenze, 50134, Italy
Kyunggi, Goyang 411-764, South Korea
Seoul, 135-230, South Korea
Barcelona, 08907, Spain
EUI-planta 2, Pg. Vall d'Hebron 119-29, Barcelona, 08035, Spain
San Martin de Porres, 4, Madrid, 28035, Spain
Investigational Site, United Kingdom
Lower Lane, Fazakerly, Liverpool, L9 7LJ, United Kingdom