The aim of this pilot study is to evaluate MBCP performance in bone regeneration after osteonecrosis biopsy of the femur head. This technic may prevent the neck of the femur bone weakness following the healthy area drilling, thanks to a bone reconstruction at the expense of the biomaterial.

Twelve patients will be enrolled in this study and evaluation of infection and inflammation of the drilled area, pain and hip function will be assessed during a one year follow up. Bone reconstruction will be evaluated with scanner and radiography.

Inclusion Criteria:

• femur head osteonecrosis (1 to 2 level in ARCO scale)
• signed informed consent

Exclusion Criteria:

• primary bone infection
• femur head sphericity loss
• cancer, diabetes, tuberculosis previous history
• HIV, Hepatitis B, Hepatitis C infection
• drepanocytosis
• current corticotherapy
• current immunosuppressive therapy
• innate or acquired immune deficience
• pregnancy or lack of efficient contraception
• current participation in an other study