The main objective of this study is to compare the sensitivity and specificity of a new system for analyzing the electrocardiogram (ECG) to the sensitivity and specificity of a conservative treadmill test in asymptomatic subjects, classified by Framingham score as moderate to high risk. Subjects will perform a routine exercise test with the addition of another set of electrodes to record high resolution ECG. All subjects will perform a stress echocardiography. The result of the routine ECG analysis will be compared to the new system and to the echocardiography results.

Inclusion Criteria:

• A patient referred to annual screening check
• Classified as being at intermediate or high risk for the development of cardiovascular disease by the Framingham score.
• Signed an Informed Consent Form

Exclusion Criteria:

• A subject who cannot or should not perform an exercise test.

Primary prevention program