Detection of Coronary Artery Disease Using Analysis of High Frequency QRS: The HyperQ Registry

Detection of Coronary Artery Disease Using Analysis of High Frequency QRS: The HyperQ Registry

This will be a registry study that will enroll patients referred for an ECG treadmill test with nuclear myocardial perfusion imaging (MPI). The high frequency QRS (HFQRS) information will be recorded and analyzed automatically and simultaneous with the standard ECG signals by the HyperQ System. Results of subsequent tests performed on each patient will be collected and used to enhance the reliability of designating each patient as a CAD-negative (i.e., no significant coronary artery disease) or a CAD-positive (i.e., significant coronary artery disease).

Inclusion Criteria:

• 18 years or older
• Referred for exercise MPI due to suspected coronary artery disease

Exclusion Criteria:

• Acute Coronary Syndrome (Unstable angina/NSTEMI/STEMI)
• Pre-excitation syndrome
• QRS duration > 120 ms
• Atrial Fibrillation or significant ventricular arrhythmia
• Treatment with Digoxin
• Pacemaker with 100% pacemaker dependence