Comparison of automatic CPAP with fixed CPAP in patients with OSAS

The polysomnography is divided into two parts, randomly assigned:

• in one part, the patient uses the automatic CPAP device in titration mode
• in the other part, the patient uses the CPAP device, in fixed mode according to the prediction formula

Inclusion Criteria:

• Patients with proven Obstructive Sleep Apnea Syndrome
• Apnea-hypopnea-index > 20/h
• Awaking index > 30/h

Exclusion Criteria:

• Severe nasal obstruction
• Hypoventilation
• Excessive sleep fragmentation caused by non-respiratory factors
• COPD (FEV1/FVC < 65%)
• CPAP compliance < 3h per night
• Insufficient sleep time (< 2h TST) during one of both parts of the split night CPAP-titration
• Patients needing > 16 mbar CPAP pressures