Prospective, Multi-Center Survey Study of Children and Adolescents With Craniopharyngioma
Prospective, Multi-Center Survey Study of Children and Adolescents With Craniopharyngioma
RATIONALE: Collecting information on how craniopharyngioma is diagnosed and treated may help doctors predict a patient's response to treatment and help plan the best treatment. It may also help identify the intermediate- and long-term effects of treatment.
PURPOSE: This clinical trial is collecting information on diagnosis, treatment, and quality of life of young patients who are undergoing surgery for craniopharyngioma.
OBJECTIVES:
Primary
Secondary
OUTLINE: This is a multicenter study.
Patients undergo neurologic, endocrine, and ophthalmologic tests and anthropometric diagnostic measurements. Patients then undergo 1 of the following surgical procedures: total resection; incomplete, subtotal, or partial resection; biopsy; or cyst pressure release. Patients whose tumor relapses may undergo a second resection and/or radiotherapy.
Quality of life is assessed at baseline and then periodically thereafter.
After surgery, patients are followed periodically.
PROJECTED ACCRUAL: A total of 120 patients will be accrued for this study.
DISEASE CHARACTERISTICS:
Diagnosis of primary craniopharyngioma by MRI and CT scan (initial diagnosis)
PATIENT CHARACTERISTICS:
Performance status
Life expectancy
Hematopoietic
Hepatic
Renal
PRIOR CONCURRENT THERAPY: Not specified
Feldkirch-Tisis, A-6807, Austria
Schwarzach, 5620, Austria
Biefeld, 33617, Germany
Greiswald, 17487, Germany
Münster, D-48149, Germany