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| ID | Type | Description | Link |
|---|---|---|---|
| 2002-P-000544/41; BWH | Registry Identifier | Medication Errors |
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| Name | Class |
|---|---|
| Brigham and Women's Hospital | OTHER |
| Boston Children's Hospital | OTHER |
| The Commonwealth Fund | OTHER |
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The purpose of this study is to determine the rates of medication errors in pediatric outpatients in 6 office practices. Further, we wish to determine the effectiveness of a computerized physician order entry (CPOE) system in reducing errors.
This study has the following 2 goals:
Aim 1: To determine the rates, types, and predictors of medication errors and ADEs.
Aim 2: To perform a trial assessing the effectiveness of an intervention (CPOE) on reducing serious medication errors.
We hypothesize that:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with prescriptions under 21 | Experimental | Pediatric visits with prescriptions. These patients parents will be given survey 1. |
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| Patients who completed Survey 1 | Experimental | Patients with prescriptions under 21 whose parents complete survey 1 will be given survey 2 |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Survey 1 | Other | During the initial survey, we reviewed dispensed medications by having parents of patients with prescriptions under 21 read the medication label. We then asked questions about potential side effects, method of medication administration, communication regarding the medication with the pharmacist and the health care provider, and demographic information. Research assistants underwent several weeks of training to ensure a standardized approach to surveys. |
| Measure | Description | Time Frame |
|---|---|---|
| Medication Errors | July 2002- August 2003 |
| Measure | Description | Time Frame |
|---|---|---|
| Adverse Drug Events | July 2002- August 2003 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Rainu Kaushal | Brigham and Women's Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Brigham and Women's Hospital | Boston | Massachusetts | 02120 | United States |
No IPD will be be shared.
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| ID | Term |
|---|---|
| D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
| ID | Term |
|---|---|
| D007945 | Leukemia, Lymphoid |
| D007938 | Leukemia |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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We performed a prospective cohort study of patients under age 21 from 6 office practices. Data collection methodologies included duplicate prescription review, 2 surveys, and chart review. All data were reviewed for medication errors, including those with the potential for harm (near misses) and those that actually caused harm (preventable ADEs). In addition, data were reviewed for harm from medications that were not associated with an error (nonpreventable ADEs). All ADEs were further characterized according to types and potential prevention strategies.
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| Survey 2 | Other | If the parent completed the initial survey, we attempted a second survey 2 months after the index visit to capture persistent symptoms. Surveys were translated and back translated into Spanish and Cambodian and conducted by fluent bilingual interviewers. Surveys were pretested and revised based on 2 focus groups of parents representing a broad array of socioeconomic backgrounds. |
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| D006402 |
| Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D008232 | Lymphoproliferative Disorders |
| D008206 | Lymphatic Diseases |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |