Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Brigham and Women's Hospital | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The study will measure the effect of basic clinical decision support on medical errors and adverse drug events in the ambulatory setting.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Routine Care | Placebo Comparator | Usual care of patients in the ambulatory setting |
|
| Basic Clinical Decision Support | Experimental | Providers use basic clinical decision support |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Basic Clinical Decision Support | Other | The computerized physician order entry (CPOE) intervention provides physicians with a menu of medications from the formulary, default doses, and a range of potential doses for each medication. Physicians were required to enter dosage, route, and frequency for all orders. Also, CPOE ensured that all orders were legible and included the prescribing physician's signature. For a number of medications, the system displayed relevant laboratory results on the screen at the time of ordering. Other features included consequent orders, which are orders that should follow from other orders, and drug-allergy checking, drug-drug interaction checking, and drug-laboratory checking. This included checking for the most frequent drug allergies, about 80 carefully selected drug-drug interactions, and several drug-laboratory combinations |
| Measure | Description | Time Frame |
|---|---|---|
| Adverse Drug Events | Adverse drug events are measured through use of a computerized surveillance system augmented by focused structured human review | 6 months |
| Medical Errors | Medical Errors are identified through a computerized surveillance system with structured human review | 6 months |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Joseph M Overhage, MD, PhD | Indiana University | Principal Investigator |
| David Bates, MD | Brigham and Women's Hospital | Principal Investigator |
| Tejal Gandhi, MD | Brigham and Women's Hospital | Principal Investigator |
| Andrew Seger, PharmD | Brigham and Women's Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Wishard Helath Services | Indianapolis | Indiana | 46202 | United States | ||
| Partner's Healthcare |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 14552850 | Background | Hope C, Overhage JM, Seger A, Teal E, Mills V, Fiskio J, Gandhi TK, Bates DW, Murray MD. A tiered approach is more cost effective than traditional pharmacist-based review for classifying computer-detected signals as adverse drug events. J Biomed Inform. 2003 Feb-Apr;36(1-2):92-8. doi: 10.1016/s1532-0464(03)00059-5. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Routine Care | Other | Routine Care |
|
| Boston |
| Massachusetts |
| 02115 |
| United States |