Performance of Acceleromyography With and Without Preload

Performance of Acceleromyography With and Without Preload During Neuromuscular Blockade

The purpose of this study is to examine the precision, bias and limits of agreement when monitoring the neuromuscular block with acceleromyography with and without preload and compare the method to the gold standard, mechanomyography.

Inclusion Criteria:

• ASA I-III
• General anesthesia > 1 hour
• Surgery under supine position with possibility of monitoring the neuromuscular block in both arms (thumbs)
• Written informed content

Exclusion Criteria:

• Neuromuscular disorders, hepatic and renal dysfunction
• Medication expected to interfere with the neuromuscular blocking agent
• Allergy to any medication used during anesthesia
• Body weight less or exceeding 20% of the ideal body weight
• Pregnancy or breastfeeding