Comparison of Acceleromyography (AMG) and Mechanomyography (MMG) for Establishing Potency of Neuromuscular Blocking Agents

Comparison of Acceleromyography and Mechanomyography for Establishing Potency of Neuromuscular Blocking Agents, A Randomized Controlled Study

The purpose of this study was to compare two methods for neuromuscular monitoring, acceleromyography and mechanomyography for establishing the dose-response relationship and the potency of a neuromuscular blocking agent using rocuronium as an example. We hypothesized that there would be no significant difference between potencies estimated using acceleromyography and mechanomyography.

Inclusion Criteria:

• ASA I-III
• Ideal weight +/-20%
• Both arms available for neuromuscular monitoring
• Surgery in supine position
• Participated surgery time more than 30 min

Exclusion Criteria:

• Pregnant and breast-feeding women
• Patients with known illness or use of medications known to influence the neuromuscular transmission
• Known significant renal or hepatic dysfunction
• Allergy to medications used in the study