Clinical Trial to Assess the Influence of Gestational Stage and Maternal Age on Arterial Stiffness of the Mother

An Open Clinical Trial to Assess the Influence of Gestational Stage and Maternal Age on Arterial Stiffness of the Mother (Hormonal and Age Related Changes of the Aortal Elasticity)

This is a single-centre, open, parallel-group study with three age groups; no study medication or intervention will be provided. This is a longitudinal follow-up of physiological parameters.

The subjects will be investigated as outpatients. For each subject, 4 individual dates with a duration of approximately 30 minutes each are scheduled - at the end of the first trimenon, at the end of the second trimenon, 4 weeks prior to the calculated date of birth, and 6 weeks after the effective date of birth.

Inclusion Criteria:

• Pregnant women without major concomitant disease

• Willing and able to provide informed consent

• Age (three age groups):

  • 20 to 22 years
  • 30 to 32 years
  • 40 to 42 years

Exclusion Criteria:

• Non pregnant women
• Men
• No informed consent
• Age not included in inclusion criteria
• Major concomitant disease