Cognitive Effects of Darifenacin and Oxybutynin Extended Release in Volunteers Aged 60 and Over

Cognitive Effects of Darifenacin and Oxybutynin Extended Release in Volunteers Aged 60 and Over

The purpose of this study is to explore the possible cognitive effects of darifenacin modified release and long-acting oxybutynin.

Inclusion Criteria:

• Males and females aged 60 and over
• United States English as a primary language
• Given written informed consent by signing and dating an informed consent form prior to study entry

Exclusion Criteria:

• Current diseases in which the use of anti-cholinergic drugs is contraindicated, including the use of drugs with anti-cholinergic effects
• Volunteers with history of urinary retention or current bladder outlet obstruction, as determined by the investigator

Other protocol defined inclusion/exclusion criteria may apply.

- Current use of drugs known to effect memory and cognition Other protocol-defined inclusion/exclusion criteria may apply