Comparison of Vascular Effects After Therapy With Irbesartan and Atorvastatin.

Characterization of Local Vascular Effects of Angiotensin II and Histamine After Treatment With Irbesartan and Atorvastatin.

Vascular responses to angiotensin II and histamine are compared before and after 30 days of systemic treatment with either irbesartan 150 mg or atorvastatin 20 mg.

Vascular responses to angiotensin II and histamine are compared before and after 30 days of systemic treatment with either irbesartan 150 mg or atorvastatin 20 mg.

Inclusion Criteria:

• healthy subjects
• no relevant disease
• amendment: hypercholesterolaemic subjects

Exclusion Criteria:

• any relevant disease