The BEAUTIFUL Study: Effects of Ivabradine in Patients With Stable Coronary Artery Disease and Left Ventricular Systolic Dysfunction

Effects of Ivabradine on Cardiovascular Events in Patients With Stable Coronary Artery Disease and Left Ventricular Systolic Dysfunction. A Three-year Randomised Double-blind Placebo-controlled International Multicentre Study.

The aim of this study is to test whether ivabradine is able to reduce cardiovascular events when given to patients with coronary artery disease and impaired heart function.

Inclusion Criteria:

• Coronary artery disease
• Left ventricular systolic dysfunction
• Sinus rhythm: heart rate (HR) >= 60 beats per minute (bpm)

Exclusion Criteria:

• Unstable cardiovascular condition
• Severe congestive heart failure