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| ID | Type | Description | Link |
|---|---|---|---|
| AOM 03123 | |||
| DGS 2004/0276 |
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| Name | Class |
|---|---|
| Association des Réseaux Bronchiolite | OTHER |
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The purpose of this study is to determine whether chest physiotherapy with forced expiratory technique reduces delay of healing in acute bronchiolitis of children between 15 days and 24 months of age.
Bronchiolitis is the most common lower respiratory infection in infants, and the respiratory condition leading to the majority of hospital admissions in young children. It is also probably the most common serious illness of childhood lacking evidence-based treatment. Evidence against the effectiveness of chest physiotherapy with vibration and postural drainage techniques has been described but forced expiratory technique, as described in France, has never been evaluated.
The investigators hypothesised that forced expiratory technique was able to reduce the duration of respiratory distress.
Comparison(s): The investigators compare physiotherapy with forced expiratory techniques to simple aspiration of naso-pharyngeal secretions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A | Experimental | Chest Physiotherapy with Forced Expiratory Technique |
|
| B | Active Comparator | Aspiration |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chest Physiotherapy with Forced Expiratory Technique | Procedure | Chest Physiotherapy with Forced Expiratory Technique |
|
| Measure | Description | Time Frame |
|---|---|---|
| Delay for obtention of healing defined by all of these parameters at least 8 hours in a row : pulse oxymétry >94% AND normal feeding AND specific respiratory distress score lower than one as described in the protocol AND normal respiratory rate | obtention |
| Measure | Description | Time Frame |
|---|---|---|
| Safety of the forced expiratory technique | during hospitalisation | |
| Comparison of pulse oxymetry before/after chest physiotherapy | during hospitalisation | |
| Quality of Life Scale |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Vincent Gajdos, MD | Assistance Publique - Hôpitaux de Paris | Principal Investigator |
| Philippe Labrune, MD - PhD | Assistance Publique - Hôpitaux de Paris | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jean Verdier Hospital | Bondy | 93140 | France | |||
| Ambroise Paré Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15846736 | Background | Perrotta C, Ortiz Z, Roque M. Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old. Cochrane Database Syst Rev. 2005 Apr 18;(2):CD004873. doi: 10.1002/14651858.CD004873.pub2. | |
| 37010196 | Derived | Roque-Figuls M, Gine-Garriga M, Granados Rugeles C, Perrotta C, Vilaro J. Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old. Cochrane Database Syst Rev. 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6. |
| Label | URL |
|---|---|
| sponsor web site | View source |
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| ID | Term |
|---|---|
| D001990 | Bronchiolitis, Viral |
| ID | Term |
|---|---|
| D001988 | Bronchiolitis |
| D001991 | Bronchitis |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| Nasopharyngeal Aspiration | Procedure | Nasopharyngeal Aspiration |
|
| on discharge |
| Boulogne-Billancourt |
| 92100 |
| France |
| Antoine Béclère Hospital - Pediatric Department | Clamart | 92140 | France |
| Kremlin Bicetre Hospital | Le Kremlin-Bicêtre | 94270 | France |
| Trousseau Hospital | Paris | 75012 | France |
| Necker - Enfants Malades Hospital | Paris | 75015 | France |
| Robert Debré Hospital | Paris | 75019 | France |
| 20927359 | Derived | Gajdos V, Katsahian S, Beydon N, Abadie V, de Pontual L, Larrar S, Epaud R, Chevallier B, Bailleux S, Mollet-Boudjemline A, Bouyer J, Chevret S, Labrune P. Effectiveness of chest physiotherapy in infants hospitalized with acute bronchiolitis: a multicenter, randomized, controlled trial. PLoS Med. 2010 Sep 28;7(9):e1000345. doi: 10.1371/journal.pmed.1000345. |
| D014777 |
| Virus Diseases |
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |