The purpose of this study is to assess the effect of an aqueous nasal spray investigational compound GW685698X compared to placebo on the hypothalamic pituitary adrenocortical (HPA) axis system in children 2 to 11 years of age with perennial allergic rhinitis.

Inclusion criteria:

• Diagnosis and history of perennial allergic rhinitis.
• Must be willing to stay overnight in the clinic at the beginning and end of the study for the collection of urine and blood samples over 24 hours.
• Must comply with all study procedures and be literate.

Exclusion criteria:

• Significant concurrent medical conditions.
• Certain medications such as corticosteroids and allergy medications.

Patient-level data for this study will be made available through www.clinicalstudydatarequest.com following the timelines and process described on this site.