The primary objective of this study is to compare the efficacy and safety of GW685698X 100mcg once daily (QD) aqueous nasal spray with vehicle placebo nasal spray in adult and adolescent subjects (12 years of age and older) with perennial allergic rhinitis (PAR).

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Once-Daily, Intranasal Administration of GW685698X Aqueous Nasal Spray 100mcg for 4 Weeks in Adult and Adolescent Subjects (12 years of age and older) with Perennial Allergic Rhinitis (PAR)

Inclusion criteria:

• Diagnosis of perennial allergic rhinitis (PAR).
• Must comply with study procedures and be literate.

Exclusion criteria:

• Significant concomitant medical conditions.
• Use of corticosteroids.
• Use of allergy medications and some other medications during the study.
• Current tobacco use.
• Clinically significant abnormal ECG or laboratory abnormality.