Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1

Cocaine Relapse Prevention II

To study of classical conditioning mechanisms associated with arousal, craving and cocaine use.

This is a single-site, double-blind, placebo-controlled crossover study of classical conditioning mechanisms associated with arousal, craving and cocaine use.

Inclusion Criteria:

• Be English-speaking volunteers who are cocaine dependent
• Be non-treatment seeking at the time of the study
• Meet DSM-IV criteria for cocaine dependence
• Have ECG showing normal sinus rhythm, normal conductivity, and non clinically significant arrhythmias
• Females must provide a negative pregnancy test and agree to use birth control
• Have baseline laboratory tests within normal limits

Exclusion Criteria:

• Please contact site for more information