Black Cohosh Extract in Postmenopausal Breast Health

The Effect of Black Cohosh Extract on the Human Breast

The purpose of the study is to determine if black cohosh extract (BCE) administration in symptomatic postmenopausal women results in estrogenic stimulation of the breast, as determined by estradiol, pS2, FSH, LH, and PSA levels in nipple aspirate fluid.

As in Brief Summary

• Postmenopausal females
• 20 months since any breastfeeding
• Active postmenopausal symptoms, i.e., hot flashes
• At least 6 months since last menstrual period or have had a hysterectomy with both ovaries removed
• Able to make 4 visits during the trial to the study clinic in Columbia, Missouri