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This study seeks to document differences in nasal irritant sensitivity within the population. The investigators are interested in knowing whether age, gender, and allergy status (nasal allergies) predict nasal irritant sensitivity. This is important in understanding symptom reporting patterns in air pollution situations (particularly in so-called "problem buildings"), as well as in understanding the reflex mechanism of a response of the nose to irritants (e.g., nasal congestion).
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nasal irritation thresholds and irritant provocation | Procedure |
Inclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Upper Airway Biology Laboratory | Richmond | California | 94804 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 9648699 | Background | Shusterman DJ, Murphy MA, Balmes JR. Subjects with seasonal allergic rhinitis and nonrhinitic subjects react differentially to nasal provocation with chlorine gas. J Allergy Clin Immunol. 1998 Jun;101(6 Pt 1):732-40. doi: 10.1016/S0091-6749(98)70302-1. | |
| 11171519 | Background | Shusterman D, Murphy MA, Balmes J. The influence of sex, allergic rhinitis, and test system on nasal sensitivity to airborne irritants: a pilot study. Environ Health Perspect. 2001 Jan;109(1):15-9. doi: 10.1289/ehp.0110915. |
| Label | URL |
|---|---|
| Website of UCSF Upper Airway Biology Laboratory | View source |
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| ID | Term |
|---|---|
| D012221 | Rhinitis, Allergic, Perennial |
| D012220 | Rhinitis |
| ID | Term |
|---|---|
| D065631 | Rhinitis, Allergic |
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
| D012130 | Respiratory Hypersensitivity |
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| D010038 | Otorhinolaryngologic Diseases |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |