Comparison of Early-stage Outcomes of Spontaneous Drainage Versus Negative-pressure Drainage Monitoring in Patients Undergoing Coronary Artery Bypass Grafting: a Prospective Randomized Controlled Study
Comparison of Early-stage Outcomes of Spontaneous Drainage Versus Negative-pressure Drainage Monitoring in Patients Undergoing Coronary Artery Bypass Grafting: a Prospective Randomized Controlled Study
Cardiovascular surgery clinics currently employ drainage monitoring methods involving both negative pressure and non-negative pressure systems. Literature reviews indicate that while drainage monitoring using negative pressure has been evaluated in thoracic surgery studies, it has not been assessed in the context of cardiovascular surgery patients. This study was designed to determine the risk-benefit profile of negative pressure drainage monitoring in patients undergoing open-heart surgery and to ascertain whether negative pressure influences the incidence or volume of postoperative tamponade or pericardial effusion.
During the routine postoperative monitoring of chest tube drainage, patients in the study group will undergo negative pressure drainage; a pressure of approximately -10 mmHg will be applied to the drain site for 48 hours via a hose connected to the hospital's central negative pressure system. Apart from this, all groups will receive standard postoperative care for Coronary Artery Bypass Graft patients, with no other differences in procedures, medications, or treatments between the groups. Negative pressure drainage is already a standard practice in the clinics involved.
Drainage output and early-stage complications (atrial fibrillation, pneumothorax, pleural effusion) will be monitored over the first 48 hours for a total of 400 patients (200 per study group). Subsequently, prior to discharge, patients will undergo echocardiography to assess for pericardial effusion and evaluate the ejection fraction. Finally, patients will be monitored for major complications-such as re-exploration for tamponade or bleeding, ECMO use, wound site revision, or mortality-up to one month post-operation.
No additional clinic visits or appointments will be required for the patients during this process.
Inclusion Criteria:
Exclusion Criteria: