DBPCT Effects of Omega-3 FA on Memory and Cognition in Peri- and Menopausal Women

A Randomised, Double-Blind, Placebo-Controlled Trial Investigating the Effects of Omega-3 Fatty Acids on Memory and Cognition in Perimenopausal and Menopausal Women

The goal of this clinical trial is to learn if daily omega-3 supplementation improves memory and cognitive function in perimenopausal and menopausal women aged 40-60 years. It will also assess whether omega-3 supplements influence menopausal symptoms, stress levels, and sleep patterns.

The main questions it aims to answer are:

1. -Does omega-3 supplementation improve memory and cognitive performance?
2. - Does omega-3 supplementation affect menopausal symptoms, stress, and perceived memory changes? 3- Are there any differences in sleep patterns during supplementation?

Researchers will compare omega-3 supplements to a placebo to see if omega-3 improves memory and cognition.

Inclusion Criteria:

• Be female and aged between 40-60 years
• Be experiencing perimenopause or menopause
• Access to reliable internet connection and a device to complete online questionnaires and cognitive assessments
• Be prepared to take a daily omega-3 supplement or placebo for 12 weeks
• Be prepared to complete pre- and post- intervention testing and questionnaires
• Speak English fluently to confirm they can complete cognitive tests to the best of their ability

Exclusion Criteria:

• Have diagnosed psychiatric or neurological condition (dementia, extreme depression, schizophrenia, bipolar disorder) which could affect cognitive function
• Not currently be taking omega-3 supplements or regularly consuming fatty fish (1 portion per/week)
• Be using hormone replacement therapy (HRT)
• Have severe dietary restrictions
• Have a history of stroke, cardiovascular disease or diabetes, as these conditions influence cognitive health
• Are unable to commit to both baseline and follow-up tests after the 12-week period
• Pregnant or breastfeeding